Home and natural remedies for upset stomach 1. Drinking water Dehydration can increase the likelihood of an upset stomach. The body needs water to digest and absorb nutrients from foods and beverages efficiently. Being dehydrated makes digestion more difficult and less effective, which increases the likelihood of an upset stomach. 2. Avoiding lying down When the body is horizontal, the acid in the stomach is more likely to travel backward and move upward, which can cause heartburn. People with an upset stomach should avoid lying down or going to bed for at least a few hours until it passes. Someone who needs to lie down should prop up their head, neck, and upper chest with pillows, ideally at a 30-degree angle. 3. Ginger Ginger is a common natural remedy for an upset stomach and indigestion. Ginger contains chemicals called gingerols and shogaols that can help speed up stomach contractions. This may move foods that are causing indigestion through the stomach more q