Managing Herpes During the 1st and 2nd Trimester Pregnancy

First or Second Trimester Acquisition

• With primary genital her during the first trimester, no evidence has been reported of an increased probability of spontaneous miscarriage.

• Women who suspect to have genital herpes must be directed to a genitourinary doctor who will refute or confirm the diagnosis via viral PCR (polymerase chain reaction), advice on genital herpes management, and set up a screen for other STDs.

• On the other hand, treatment should not be delayed. The woman's management bought to be consistent with her clinical state and will typically involve using oral or intravenous (for hermitted herpes) aciclovir in doses of 400 mg thrice daily, typically for five days. The use of such agent is linked to a decrease in the severity and duration of the herpes symptoms and a reduction in the period of viral shedding.

For use in pregnant women, aciclovir is not licensed but is deemed as safe and has not been linked with a rise in birth defect incidence. Transient neutropenia in new-borns has been reported, but there have been no clinically substantiated adverse neonatal or maternal effects reported. Aciclovir is tolerated during pregnancy.

• A dose adjustment is not necessary for treatment courses. There's no evidence of a rise in birth defect risk with aciclovir, valaciclovir, or famciclovir if utilized in the initial trimester.

• Safety data for aciclovir could be generalized to valaciclovir during late pregnancy since it's the valine ester, yet as there's less experience and knowledge with the use of famciclovir or valaciclovir, they are not approved as a first line treatment.

• The obstetrician advised to be informed.

• Topical lidocaine 2% gel and paracetamol can be provided as symptomatic relief. There's no evidence that either agent is damaging to pregnancy in standard doses.

• Women who suspect to have genital herpes and are having a midwifery-led care bought to be directed for examination by an obstetrician, preferably after examination by the genitourinary medicine doctor.

• If the delivery does not follow within the following six weeks, the pregnancyought to be managed expectantly as well as vaginal delivery anticipated. No evidence has been reported that HSV contracted during pregnancy is linked to an increased incidence of congenital abnormalities.

• After the first or second trimester acquisition, suppressive Acyclovir 400 mg thrice a day from 36 weeks of gestation decreases HSV lesions at term and there before the necessity for delivery by C-section. Moreover, it has been established to decrease asymptomatic viral shedding (comparable results have been observed with Valaciclovir, although valaciclovir is not recommended for use during pregnancy considering the insufficient experience with the agent's use).

While herpes is not necessarily transmitted during pregnancy, we still can not ignore the risks and every expecting mother should know how to prevent transmitting the disease during pregnancy. Living a clean and healthy lifestyle and regularly taking anti-viral drugs can definately help in preventing herpes infection. It would be best to research more about the subject for the best results.

Source by Louis V Lim

from Home Solutions Forev https://homesolutionsforev.com/managing-herpes-during-the-1st-and-2nd-trimester-pregnancy/
via Home Solutions Forev on Tumblr



from Home Solutions FOREV https://homesolutionsforev.wordpress.com/2019/04/14/managing-herpes-during-the-1st-and-2nd-trimester-pregnancy/
via Brenda Lawrence on Weebly

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